23andAli

At a Las Vegas gala celebrating Muhammad Ali’s 70th birthday, we premièred the video "Give Us Your Hand," featuring the boxing legend and his involvement with 23andMe’s Parkinson’s Disease Research Initiative. By Emily Drabant As the Research Manager for the 23andMe Parkinson’s Community, I spend my ...

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Studies of Extreme Longevity Extremely Challenging

By David Hinds, Chuong Do, and Shirley Wu In January we wrote about the challenging search for genetic influences on human longevity, touching on two of the most recent studies as examples of how elusive solid findings have been. Because one of these studies was a new version of a paper that was previously ...

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Did You Know? One in Twelve African Americans has Sickle Cell Trait

Sickle Cell Celebrities A number of famous individuals have suffered from sickle cell anemia including Miles Davis, perhaps the most famous jazz musician to have lived (some consider his platinum-selling album Kind of Blue to be THE jazz album), and Tionne 'T-Boz' Watkins, a singer and founder of the ...

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What Does Your Doctor Know About Genetic Testing For Drug Response?

Your doctor, undoubtedly, knows quite a lot.  She went through four grueling years of medical school, passed a rigorous set of board exams, and completed at least one intensive residency in her speciality.   What may surprise you, however, is that she may not know very much about pharmacogenetics, the study ...

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SNPWatch: Genetic Variants Linked to Male Infertility in Asians

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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SNPwatch: KIF6 Tangos with LDL Cholesterol and Coronary Heart Disease

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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Stories on Every Branch of the Family Tree

Every family has its stories. We just don’t know them all. That’s where genealogy comes in. Through census and military records, notes in family bibles, or conversations with older relatives we can recover some of those family histories. But where memories and traditional paper records fail, we now have a new ...

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The Debate Over Clopidogrel Continues

In December a new study created quite a stir in the already-volatile clopidogrel research community. Clopidogrel (trade names Plavix®) is a commonly prescribed anti-clotting drug. It is inactive in the body until a protein encoded by the gene CYP2C19 converts the drug to its active form. Some people are able ...

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Seeking the Secrets of the Super Long-Lived

With analytical contributions from 23andMe Scientist David Hinds For all human history people have been obsessed with their own mortality. Early explorers searched the globe for the mythical “fountain of youth,” and now scientists are turning that exploration inward to look at the genomes of people who’ve ...

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My Heart, My Family, and MYBPC3

By Arnab Chowdry, Senior Scientific Software Engineer at 23andMe Having been young and healthy for the majority of my life, I haven’t had many opportunities to interact with our health care system.  Not too long ago I was a sedentary, slightly-overweight, South Asian man entering my thirties.  I had some ...

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