Author: ErinC

Globules of Globules of Globules: Research Reveals How Our Cells Pack in All That DNA

A segment of chromosome 14 folded to reveal a fractal curve using Origami. Designed and folded by Jason Ku. Photo by Erik Demaine. How do you get three billion pairs of As, Cs, Ts and Gs—about six feet worth of DNA—into the nucleus of a tiny cell? Most students of biology would answer by saying that ...

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Researchers Discover the True Identity of the “Royal Disease”

Empress Alexandra Feodorovna and Prince Alexei, 1911. The princes of early 20th century Europe had a problem.  The source of their wealth and power -- the royal blood coursing through their veins -- could also sentence them to an early death. A mutation that spontaneously arose in the DNA of Britain's ...

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SNPwatch: Researchers Find More Genetic Variants Associated With Prostate Cancer

In the United States, prostate cancer affects about one in every six men.  Genomewide association studies aimed at finding common genetic variants associated with this common disease have been particularly successful. More than a dozen SNPs have been associated with prostate cancer, but researchers calculate ...

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SNPwatch: More Evidence That Genetic Variations are Important for Hepatitis C Infection and Treatment

Unlike the flu virus, which the body is generally able to fight off completely, infection with hepatitis C is often chronic.  That means for most of the three to four million people worldwide who are newly infected each year the virus will persist in the body, where it greatly increases risk for chronic ...

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SNPwatch: Largest Alzheimer’s Genetic Studies To Date Identify Three New Susceptibility Genes

Despite years of effort and millions of dollars in research funding, only one gene, APOE, has been conclusively associated with Alzheimer's disease risk so far.  But now the results of two of the largest Alzheimer's studies ever provide convincing evidence that three more genes affect risk for the ...

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Surprisingly Skinny Mice Could Point the Way to Obesity and Diabetes Treatments

Scientists who are studying mice with a mutation that makes them resistant to obesity even in the face of a high-fat diet may have identified a new way to treat both obesity and diabetes. Carrying extra weight is known to trigger a state of chronic, low-grade inflammation in the body, which can lead to ...

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SNPwatch: Genetic Variation Associated With Addiction In Caucasian Women

Although environment plays a major part in addiction — you can't get hooked on something you've never tried — genetics plays a substantial role in determining whether a person who does use a drug will become addicted to it. A few DNA variations have been identified that seem to increase the odds a person ...

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More Evidence that Genetics Can Reduce the Efficacy of Anti-Clotting Medication Clopidogrel

A new report in the Journal of the American Medical Association adds to the mounting evidence that genetic variations impact the efficacy of clopidogrel (Plavix®), a drug used to prevent blood clots in people who have had a heart attack or stroke and also those with peripheral artery disease and unstable ...

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SNPwatch: Genetic Variants Associated With Risk Of Childhood Acute Lymphoblastic Leukemia Identified

SNPwatch gives you the latest news about research linking various traits and conditions to individual genetic variations. These studies are exciting because they offer a glimpse into how genetics may affect our bodies and health; but in most cases, more work is needed before this research can provide ...

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SNPwatch: Genetic Variation Predicts Hepatitis C Treatment Success

SNPwatch gives you the latest news about research linking various traits and conditions to individual genetic variations. These studies are exciting because they offer a glimpse into how genetics may affect our bodies and health; but in most cases, more work is needed before this research can provide ...

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