Author: Shwu

Ancestry at 23andMe: Sheridan’s Global Origins

In her first ancestry foray, Sheridan* learned about her Maternal Line. Through her friend Mesut, she also learned about the Paternal Line feature. But these analyses only told her about a tiny part of her DNA. Other features at 23andMe use DNA contained in the other 22 pairs of chromosomes -- called ...

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Ancestry at 23andMe: Introducing Sheridan

Meet Sheridan*. She's a 27 year old female who signed up for 23andMe during one of our sales. Adopted at eight months, she has no information about her biological roots and the adoption agency has no records other than where she was found -- on the steps of a church in a small town near Atlanta, Georgia. She ...

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Guidelines From Professional Human Genetics Societies and 23andMe Policies

by Uta Francke, M.D. The European Society of Human Genetics (ESHG) has issued a policy statement on direct-to-consumer (DTC) genetic testing for health-related purposes. Published in the Society's journal, the European Journal of Human Genetics, the statement addresses a multitude of issues and proposes ...

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Ancestry at 23andMe: What Can You Learn?

Genetic testing is not a concept that most people encounter outside of popular TV shows and so when you hear about services such as 23andMe’s, you might be wondering what exactly it is you’re getting. Even after you’ve signed up and have your data back, you might not know where to start exploring or how to ...

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SNPwatch: Researchers Link Migraine Susceptibility to Genes Involved in Glutamate Regulation

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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SNPwatch: Genetic Variant Contributing to Melanoma Risk has Different Effects on Mole Count Depending on Age

Melanoma is a rare but deadly form of skin cancer. Known risk factors include pale skin, large numbers of moles (also known as nevi), and prolonged sun exposure. Nevus count has a strong genetic component and researchers have already identified some genetic variants that influence the trait. In a new study ...

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SNPwatch: Two Studies Connect More Immune System Genes to Rheumatoid Arthritis

Rheumatoid arthritis is a common autoimmune disease in which the individual's own immune system attacks the lining of the joints, causing stiffness and muscle aches. Like other autoimmune diseases, development of rheumatoid arthritis is likely caused by a complex combination of genetic and environmental ...

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SNPwatch: Believe It Or Not, Researchers Find Genetic Variant Linked To Gullibility

We’ve all fallen for a prank at some point or another – whether it be “hey, your shoe’s untied” or getting surprised at your birthday party after your friend asks you to “just pick up something from the house.” Most people become more wary as they get older but other people manage to remain fundamentally ...

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SNPwatch: Genetic Variant Associated With Lone Atrial Fibrillation

Atrial fibrillation (AF) is the most common irregular heart rhythm, affecting one in four people over the age of 40. While not usually life-threatening on its own, individuals with the condition are at increased risk of stroke and heart failure. AF appears most frequently in older, male individuals with a ...

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SNPwatch: Genetic Association Study of Leprosy Yields New Insights into an Ancient Disease

Leprosy is a chronic, disabling disease caused by a bacterium (Mycobacterium leprae) that infects only humans and armadillos. The disease affects the skin and peripheral nerves, leading to sores, numbness in the limbs, muscle weakness, and, in severe cases, disfiguring nodules on the skin. Known since ...

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