Category: 23andMe Research

SNPwatch: Genetic Variations Associated with Autoimmune Form of Hair Loss, Alopecia Areata

Alopecia areata is a form of hair loss many people are unfamiliar with, although the condition affects more than five million people in the United States.  Unlike male (or, more rarely, female) pattern baldness, which is thought to be caused by hormones, alopecia areata results from an autoimmune attack on ...

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SNPwatch: Four More DNA Variations Linked to Testicular Cancer

British researchers have identified four new genetic variants that may influence a male's risk for testicular cancer.  These results, published recently in the journal Nature Genetics, along with variations in three genetic regions previously identified by the same group, are beginning to shed some light on ...

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23andMe Improves Research Consent Process

Today, 23andMe is pleased to announce that we have received institutional review board (IRB) approval for our research protocol and an accompanying revised Consent Document.  This approval reaffirms that all 23andMe research efforts intended for publication protect the interests of our customers.  Our ...

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23andMe and a New Paradigm for Research

As highlighted in Thomas Goetz's new Wired article "Sergey's Search," 23andMe's innovative web-based research platform is pushing Parkinson's disease research ahead at an unprecedented pace.  With our database clocking in at 50,000 genotyped customers—a number that grows everyday—we're poised to make exciting ...

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SNPwatch: Genetic Variant Contributing to Melanoma Risk has Different Effects on Mole Count Depending on Age

Melanoma is a rare but deadly form of skin cancer. Known risk factors include pale skin, large numbers of moles (also known as nevi), and prolonged sun exposure. Nevus count has a strong genetic component and researchers have already identified some genetic variants that influence the trait. In a new study ...

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SNPwatch: New Genetic Associations Revealed for Nasopharyngeal Carcinoma

Nasopharyngeal cancer (NPC) arises in the upper part of the throat, behind the nose.  It is rare in most areas of the world—affecting only about 1 in every 100,000 people—but about 25 times more common in southern China, earning it the name "Cantonese Cancer."  NPC rates are also high in southeastern Asia, ...

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SNPwatch: Genetic Variants Associated with Risk of Paget’s Disease of Bone Identified

Aching joints and bones aren't always just a normal part of aging.  For some, they are a symptom of Paget's disease of bone (PDB), a condition that affects more than one million people over the age of 45 in the United States. Bone tissue is constantly being recycled.  As old bone is broken down, new bone ...

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SNPwatch: Two Studies Connect More Immune System Genes to Rheumatoid Arthritis

Rheumatoid arthritis is a common autoimmune disease in which the individual's own immune system attacks the lining of the joints, causing stiffness and muscle aches. Like other autoimmune diseases, development of rheumatoid arthritis is likely caused by a complex combination of genetic and environmental ...

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SNPwatch: Large Study Identifies Two More Genetic Variants Associated with Alzheimer’s Disease

Understanding Alzheimer's disease, the most common cause of dementia in people 65 years and older, is of the utmost importance as the population of the United States (and many other nations) becomes increasingly older.  Currently more than five million Americans are thought to have the disease, but by the ...

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SNPwatch: Genetic Variant May Impact Rate of Cognitive Decline in the Elderly

New research, published recently in the journal Neurology, has found the surprising result that a genetic variant previously associated with better cognitive function in young people appears to have the opposite effect as people get older. Alexandra Fiocco and colleagues from the University of California, ...

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