Tag: APOE

New Study Helps Explain Alzheimer’s Genetic Risk

Robin Smith, Health Content Scientist A report published this month in the journal Nature describes a breakthrough in scientists' understanding of Alzheimer's Disease. Researchers from Columbia University dissected the relationship between a genetic risk factor in the APOE gene and the formation of protein ...

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Brain Injury, Mental Decline, and the APOE Gene

Mounting evidence points to brain trauma as a risk factor for mental decline. Football players who’ve had multiple concussions perform worse on tests of brain function and are more likely to have memory problems later on. Repeated blows to the head can also cause certain types of dementia -- medically ...

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A Genetic Variant Protective Against Alzheimer’s

This past summer researchers announced they’d discovered a rare genetic variant that may be protective against Alzheimer’s disease. Alzheimer’s is an important topic among 23andMe customers so naturally they asked for more information about the variant. After a review of the research,  we recently released ...

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World Alzheimer’s Day

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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Genetics and the Risks from Traumatic Brain Injuries

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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Studies of Extreme Longevity Extremely Challenging

By David Hinds, Chuong Do, and Shirley Wu In January we wrote about the challenging search for genetic influences on human longevity, touching on two of the most recent studies as examples of how elusive solid findings have been. Because one of these studies was a new version of a paper that was previously ...

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SNPwatch: Large Study Identifies Two More Genetic Variants Associated with Alzheimer’s Disease

Understanding Alzheimer's disease, the most common cause of dementia in people 65 years and older, is of the utmost importance as the population of the United States (and many other nations) becomes increasingly older.  Currently more than five million Americans are thought to have the disease, but by the ...

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SNPwatch: Largest Alzheimer’s Genetic Studies To Date Identify Three New Susceptibility Genes

Despite years of effort and millions of dollars in research funding, only one gene, APOE, has been conclusively associated with Alzheimer's disease risk so far.  But now the results of two of the largest Alzheimer's studies ever provide convincing evidence that three more genes affect risk for the ...

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