Tag: Nature

Own Your Data: A Right and Responsibility for Better Health

“Citizens worldwide have too long a history of being passive players in health care -- blindly following instructions from providers.” The quote above, taken from a Nature Comment published yesterday by John Wilbanks and Eric Topol, encapsulates my motivation for co-founding 23andMe a little over 10 years ...

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Love and Science

Researchers often say it’s their love of science that drives their work, but for Eric Minikel and Sonia Vallabh it’s their love that propels the science. The married couple — both are researchers at the Broad Institute and are completing their doctorates at Harvard Medical School — helped to co-author a ...

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A Reference of Human Genetic Variation

One of 23andMe’s newest scientists, Adam Auton, had his first day on Monday, and by Wednesday had two new papers on human genetic variation published in the journal Nature. Not a bad first week of work. “It’s been a busy few days,” Adam said. The research on the papers was not done at 23andMe, of ...

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Mother Europe

The story of H is really the story of people in modern Europe. H refers to a maternal lineage — also known as a maternal haplogroup — that originated long ago in the Near East but expanded into Europe with the recession of the last Ice Age. H —with its dozens of subgroups — is the most prevalent haplogroup ...

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SNPwatch: Genetic Variations Associated with Autoimmune Form of Hair Loss, Alopecia Areata

Alopecia areata is a form of hair loss many people are unfamiliar with, although the condition affects more than five million people in the United States.  Unlike male (or, more rarely, female) pattern baldness, which is thought to be caused by hormones, alopecia areata results from an autoimmune attack on ...

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Genetics: Looking Back and Looking Forward

The tenth anniversary of the completion of the first draft of the human genome is approaching, apparently putting a lot of scientists in the mood for reflection on the past and speculation about the future of genetics. The journal Nature has a series of opinion articles and two news articles on the ...

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SNPwatch: Enzyme Deficiency May Protect Against Serious Hepatitis C Treatment Side Effect

People chronically infected with the hepatitis C virus currently have only one treatment option:  a combination of polyethylene glycol (PEG)-ylated interferon alpha and ribavirin (RBV).   Not only does this drug regimen fail to eradicate the virus in about half of all patients who receive it, but even when it ...

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Researchers Use SNP Analysis to Paint Picture of an Ancient Human

Artist's impression of Inuk based on genetic analysis Nuka Godfredsen/Nature Tufts of hair rescued from the permafrost in Greenland and then tucked away in a basement in Denmark for more than 20 years have given scientists their first glimpse into the genetics of an ancient human. Eske Willerslev and ...

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New Genetic Analysis Sheds Light on Origins of Indian Castes

For as long as humans have lived in complex communities, cities and civilizations, they have divided and classified their societies. Those divisions have been based on age, gender, appearance or - in many cases - occupation. In many traditional societies artisans would share the same social status; as would ...

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SNPwatch: More Evidence That Genetic Variations are Important for Hepatitis C Infection and Treatment

Unlike the flu virus, which the body is generally able to fight off completely, infection with hepatitis C is often chronic.  That means for most of the three to four million people worldwide who are newly infected each year the virus will persist in the body, where it greatly increases risk for chronic ...

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