Some of the more common thiopurine drugs: 6-Thioguanine (Lanvis®) 6-Mercaptopurine (Purinethol®) Azathioprine (Azasan®, Imuran®) You may lack the enzyme thiopurine methyltransferase (TPMT) and not even know it. For most of those who lack the enzyme, it will never be a problem, but, for those who are [...]
January 15, 2013
Do You Know How You’ll Respond to Thiopurine Medications?
November 10, 2009
SNPwatch: Genetic Variations May Impact Risk of Hearing Loss in Children Receiving Common Chemotherapy Drug
Cisplatin, a cancer chemotherapy drug first approved by the FDA in 1978, revolutionized the treatment of many types of cancer. Despite its effectiveness, in many cases doctors are forced to reduce the drug's dose, or abandon it altogether, due to serious side effects on patients' hearing. Between 10-25% [...]