Confusion Over Utility of Common Genetic Variations in Breast Cancer Risk Prediction

A paper published in the New England Journal of Medicine (NEJM) this week, entitled "Performance of Common Genetic Variants in Breast-Cancer Risk Models," has led several media outlets to declare that common genetic variants have nothing to add when it comes to predicting breast cancer risk.  Here we'll ...

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23andMe Allergy Survey: Nothing to Sneeze At

Spring is about to, well, spring.  And for many of us, that means breaking out the Benadryl® and the tissues as pollen fills the air and our allergies kick in. Allergies are part of the daily lives for one out of four Americans, making allergies more common than heart disease, cancer and diabetes ...

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NIH to Create Public Database of Genetic Tests

Today the National Institutes of Health (NIH) announced its plans to create a public database in which genetic test providers will voluntarily deposit information about their services that can then be searched by researchers, consumers, health care providers, and others. The aim of this Genetic Testing ...

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Genetic Tests Can Reduce Risks From Blood Thinner Warfarin

Editor’s note: Pending an FDA decision, 23andMe no longer offers new customers access to health reports referred to in this post. Customers who purchased prior to November 22, 2013 will still be able to see their health reports, but those who purchased after that time will not. Those customers will have ...

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FDA Adds Boxed Warning to Plavix Label to Highlight Reduced Effectiveness of the Drug In Poor Metabolizers

The U.S. Food and Drug Administration (FDA) has updated the label information for the commonly used anti-clotting medication Plavix® (clopidogrel) to stress to physicians that patients carrying certain genetic variations may not receive the full benefit from the drug. Plavix reduces the chance a harmful ...

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March is Colorectal Cancer Awareness Month

Colorectal cancer is the third most common cancer (excluding skin cancers) and the second leading cause of cancer-related deaths in the United States. Each year about 150,000 people are diagnosed with the disease. Risk factors for colorectal cancer include age (most cases occur in people over 50), ...

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SNPwatch: Researchers Identify Variations Associated with When Junior Gets His First Chompers

Researchers have identified several genetic variations associated with the timing of a baby's first tooth and the number of teeth at age one. The results, published recently in the journal PLoS Genetics, could be important for understanding more about human health than just this rite of passage all babies ...

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Don’t Miss the Final Episode of Faces of America this Wednesday!

Faces of America is a four-part series in which Harvard scholar Henry Louis Gates, Jr. uses genealogy and genetics to explore the family histories of 12 renowned Americans in an effort to understand what made the United States the place it is today. The final episode, "Know Thyself" airs this Wednesday ...

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SNPwatch: Genetic Variant Associated With Lone Atrial Fibrillation

Atrial fibrillation (AF) is the most common irregular heart rhythm, affecting one in four people over the age of 40. While not usually life-threatening on its own, individuals with the condition are at increased risk of stroke and heart failure. AF appears most frequently in older, male individuals with a ...

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Attention Human Genetic History Buffs

The journal Current Biology has a special review issue on the global genetic history of Homo sapiens.  The articles are written for a fairly technical audience, but if it's a topic you're interested in, you might want to check it out.  All of the articles are available online for free. Archaeogenetics — ...

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