23andMe’s Presentations at ASHG

This week our scientists have been busy at the American Society of Human Genetics Annual Meeting in San Francisco.

As promised we’re putting up links to each of the posters that we presented at the meeting. It gives you a sense of the breadth and depth of 23andMe’s research and our commitment to share our findings with our customers.

• Reactions to direct-to-consumer BRCA test results

• Genome wide association study of sexual orientation in a large, web-based cohort

Myeloproliferative neoplasms and somatic mosaicism in the 23andMe participant community

• Genetics of myopia in a participant-driven, web-based cohort

• Not a stretch: Variant near the dermal gene elastin is associated with stretch marks

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Whole-genome sequencing of 50 LRRK2 G2019S carriers discordant for Parkinson’s disease

• The power of large numbers: frequencies of of rare, pathogenic mutations in the 23andMe database

• A scalable pipeline for local ancestry inference using thousands of reference individuals

• Genetic variants associated with breast size also influence breast cancer risk

• So fresh or so clean? A genetic variant near olfactory receptor genes influences cilantro preference

• Web-based phenotyping yields replication of genetic associations with response to warfarin

• Population sampling and in vitro modeling of a 25bp deletion associated with hypertrophic cardiomyopathy

• Interpretation of variants of unknown significance using identity-by-descent in a large database of genotyped and phenotyped individuals

• A web-based initiative to accelerate research on genetics and disease in African Americans

• GWAS identifies 13 polymorphisms associated with motion sickness

• Considerations for the processing and direct-to-consumer return of exome sequences

• Evaluation of a scalable method for returning results and genetic findings from genomic research to research participants