Tag: dogs


August 9, 2012

Canine Olympians

RaceDogImage

Watching the Olympics, I am awed by the athleticism of the contestants: they compete with strength, skill and coordination that I could hardly dream of possessing. Certainly hard work and determination has played a role in each athlete’s story, but probably good genes have also contributed to their [...]

Read more…

March 23, 2012

How Did the Shar-Pei Get His Wrinkly Skin?

Figure 1 of Hitte and Webster’s 2011 PLoS Genetics paper clusters 509 dogs based on their genetic similarity. In this figure, dogs that are genetically similar to each other are grouped together, and, not surprisingly, this grouping corresponds quite well with breed (dogs of the same breed are grouped together). Some breeds do cluster together (for instance, all the retrievers are clustered together, as are the all the spaniels), but the relatively long branches connecting dogs within the same breed and the relatively short branches connecting the different breeds together is consistent with breeds which originated from a common dog gene pool long ago and have remained quite distinct. Note that the longer branches in the Boxer breed are due to the fact that the boxer genome sequence was used as a reference for selecting SNPs, rather than a reflection of true genetic distance.  Image from Vaysse A, et al. PLoS Genet. (2011) vol. 7 iss. 10 pp. e1002316.

March 23rd is National Puppy Day! How did the Shar-Pei get his wrinkly skin? The question sounds like the beginning of one of Kipling’s “Just So” stories, but this and other questions were the subject of a recent genetics study. What gives some breeds their Lilliputian legs and others their lengthy [...]

Read more…

December 30, 2009

2009 Spittoon Highlights – Part 2

iStock_000009805680XSmall

In our last post we highlighted a few of the coolest (in our opinion!) health-related developments of 2009.  But human genetics isn't all about disease.  Here are a few more favorites: The Romanovs 2009 saw the identification of the remains of the missing members of this Russian royal family, as well [...]

Read more…

August 31, 2009

Study Sniffs Out Genes Behind Doggy ‘Dos

long silky fluffy

New genetic research may explain why Fluffy is so fluffy. A study led by researchers at the National Human Genome Research Institute scanned 1,000 dogs from 80 breeds, looking for genes associated with different hair types: curly, wavy, straight, wiry, long and any combination of these. Their results, [...]

Read more…

July 17, 2009

Single Gene Responsible For Stubby Legs In Dogs

basset

On occasion, the Spittoon departs from its usual mission of bringing you the latest and greatest in human genetics news in order to report on particularly interesting discoveries in other species.  Many times these stories are about dogs and the reason is simple: dogs are awesome. Well, there is more to [...]

Read more…

November 7, 2008

Gene Links Gout in Humans with Bladder Stones in Dalmatian Dogs

smiling_dalmatian

When they eat purines, a class of chemicals that are found in many types of food and most abundant in organ meats and some types of fish and shellfish,, most mammals break them down into a substance called allantoin, which is then excreted. The only exceptions are humans, great apes and Dalmatian dogs, all of [...]

Read more…

Return to top