23andMe’s Presentations at ASHG

This week our scientists have been busy at the American Society of Human Genetics Annual Meeting in San Francisco.

As promised we’re putting up links to each of the posters that we presented at the meeting. It gives you a sense of the breadth and depth of 23andMe’s research and our commitment to share our findings with our customers.Reactions to direct-to-consumer BRCA test results

Genome wide association study of sexual orientation in a large, web-based cohort

Myeloproliferative neoplasms and somatic mosaicism in the 23andMe participant community

Genetics of myopia in a participant-driven, web-based cohort

Not a stretch: Variant near the dermal gene elastin is associated with stretch marks

Whole-genome sequencing of 50 LRRK2 G2019S carriers discordant for Parkinson’s disease

The power of large numbers: frequencies of of rare, pathogenic mutations in the 23andMe database

A scalable pipeline for local ancestry inference using thousands of reference individuals  

Genetic variants associated with breast size also influence breast cancer risk

• So fresh or so clean? A genetic variant near olfactory receptor genes influences cilantro preference

Web-based phenotyping yields replication of genetic associations with response to warfarin

Population sampling and in vitro modeling of a 25bp deletion associated with hypertrophic cardiomyopathy

Interpretation of variants of unknown significance using identity-by-descent in a large database of genotyped and phenotyped individuals

A web-based initiative to accelerate research on genetics and disease in African Americans

GWAS identifies 13 polymorphisms associated with motion sickness

Considerations for the processing and direct-to-consumer return of exome sequences

Evaluation of a scalable method for returning results and genetic findings from genomic research to research participants

  • This is a tremendous work that you have achieved and that you are sharing here. Congratulation.

  • Altorfer

    It’s not credent for if they say they couldn’t find any association in the GWAS of sexual orientation. That ‘s weird. Are you really sure? What’s about the ”suggestive” ones? What if these ones will grow the clear genetic associations when you have 3, 4 or 5 times more persons asked for this survey? I’m sure this will be the case!

  • Altorfer

    Table 4 Preliminary Phenotype Associations is very interesting. I have never gave tihis table any attention until today.