23andMe Releases First-of-its Kind Genetic Weight Report

Large scale genetic and non-genetic data plus machine learning, used to provide personalized portraits of how genes and lifestyle impact weightGenetic Weight report

Have you ever wondered if it’s your genes keeping you from fitting into your jeans? You’re not alone, and plenty of research shows that the genetic cards we are dealt at birth play an important role not just in our weight but in how much our bodies respond to diet and exercise. Our weight is determined by a complex combination of lifestyle, environment, and genes.

Armed with a collection of data from over 600,000 research participants, 23andMe scientists used machine learning techniques to estimate BMI based on genetics. Key results from these analyses also showed that lifestyle factors such as diet and exercise may affect weight in a way that is dependent on a person’s genetic makeup. This research resulted in a new, first-of-its kind Genetic Weight report that incorporates both genetics and lifestyle and calculates a person’s  genetic predisposition to weigh more or less than average. The report also provides insight into which lifestyle factors might make the biggest difference for a person’s own weight.

This report breaks new ground because it’s the first time that 23andMe scientists have been able to leverage the immense amount of information generously contributed by research participants for a health-related report. It is based on over 300 variants found to be associated with weight in 23andMe’s own database, and it customizes results based on age, sex, and ancestry.

23andMe scientists have also incorporated important in-house findings about lifestyle and genetics. These so-called “gene-by-environment interactions” are based on data contributed by over 45,000 research participants. Each personalized report provides a ranked list of lifestyle factors found to be associated with the biggest weight differences based on each person’s genetic result. In other words, this information shows how people’s specific genetics may influence their own responses to not only exercise and certain food choices, but also to factors like sleep and stress. This could help customers prioritize their own choices for maintaining a healthy weight.

The Genetic Weight report marks a first step towards the kind of personally tailored wellness reports 23andMe aims to provide consumers. Future reports will build on the insights found through creating a machine-learning model that leverages the massive amount of data from customers who consent to participate in research.

For more on the science behind this report see our white paper.

Genetic Weight 2

 






  • Is this report being released generally? Just not seeing it my list and am wondering if it will be there eventually.

    • 23blog

      Hi Kenneth, You should see it come up soon.

      • 23blog

        Hi Kenneth, I need to clarify this. Customers who have transitioned to the new experience will all have the report. If you haven’t not yet been transitioned to the new experience you will not be able to see the report.

        • caroline

          Hi

          When will we be transitioned to “the new experience”??

        • 23blog

          Caroline,
          If you are an international customer, that will be happening in the near future. Other customers should have all been transitioned by now. If you need help with your account, please contact our customer care team: https://customercare.23andme.com/hc/en-us

  • 23blog

    Hi Rachel,
    Sounds like you have two issues. You are waiting for your results to come in, and you have a question about your genetic weight report. You can sign in to see if your results are ready yet. Customers typically get an email letting them know when their results are ready, but you can double check. If you have gotten your results than you should also have access to the genetic weight report. If you have specific questions about your account, you can send a note to our customer care team. (https://customercare.23andme.com/hc/en-us)

  • 23blog

    A little more than a year ago, we transition US customers to the new experience. We hope to transition international customers in the coming months.

    • Does this include UK customers? We’ve had no notification that the transition is going to take effect. I understand that international customers with ancestry-only kits have been notified that they will be transitioned.

  • 23blog

    Hi Anita,
    Here is a link to more details regarding the new experience. If you are currently a US customer you should already have been transitioned. (https://customercare.23andme.com/hc/en-us/articles/212030818-I-m-a-current-customer-what-do-I-need-to-know-about-the-new-23andMe-)

    • Anita Bern

      Hi
      Thank you for the answer, sadly i am not a US customer but from Denmark. When is the upgrade scheduled for me? The page does not give a clear enough answer to satisfy my curiosity :)

      • 23blog

        Hi Anita,
        I’m sorry but I don’t have a specific time. We will update with more specifics when we have them.

  • 23blog

    Hi Jason,
    We offer health and ancestry information to customers in the UK, Canada, Denmark, Finland, Ireland, Sweden and the Neatherlands. But in other international markets we currently only offer ancestry. This does not have to do with the FDA, but is more tied to applicable regulations in those countries.

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