You may use your FSA or HSA for 23andMe health offerings. Learn more today and get started. 
Here’s some good news if you’re among the millions of people in the United States with a healthcare Flexible Spending Account (FSA) or Health Saving Account (HSA): 23andMe health offerings may be fully or partially eligible for <a href="https://www.23andme.com/fsa-hsa/">use of FSA or HSA dollars</a>. 
23andMe’s health offerings include health reports, features, and services that are part of <a href="https://www.23andme.com/dna-health-ancestry/">23andMe Health + Ancestry Service</a>, <a href="https://www.23andme.com/membership/">23andMe+ Premium</a>™ and <a href="https://www.23andme.com/total-health/">23andMe+ Total Health</a>.™ In addition, clinical lab tests and clinician fees coordinated through 23andMe are part of 23andMe’s health offerings. (See below for more detail on each of these services.)
<h2>IRS Changes to FSA and HSA in 2023 </h2>
Before diving into all that is eligible under 23andMe’s umbrella of offerings, knowing more about these flexible pre-tax spending accounts and what’s new is essential.
The IRS has significantly increased the amount of pre-tax income people can set aside in the two most common types of these accounts — Flexible Spending Accounts (FSA) and Health Saving Accounts (HSA). Like retirement savings accounts that allow people to save money with pre-tax income, these accounts are also pre-tax but earmarked for medical expenses. You can find out more about the two types of accounts <a href="https://www.irs.gov/government-entities/federal-state-local-governments/where-can-i-learn-more-about-health-savings-accounts-hsa-and-health-reimbursement-arrangements-hra">here</a>.*
The IRS recently increased the amount people can set aside for both of these types of accounts; for instance, individuals can set aside up to $3,850 in pre-tax income for the HSA account, while families can set aside $7,750.*
You can use this money for all sorts of “qualified medical expenses,” from co-pays for doctor’s visits to prescription medications to glasses and sunscreen. 
Are 23andMe’s health offerings a qualified medical expense? Yes, they are. Not too long ago, the <a href="https://permalinks.23andme.com/pdf/IRS_PLR132576_18.pdf?_gl=1*1crr0o3*_ga*MTYzNzM2NzYyNy4xNjcwODY5Nzcy*_ga_G330GF3ZFF*MTcwMTcwMjIwNy4xMjUuMS4xNzAxNzAyMjY3LjAuMC4w">IRS ruled </a>that you can use FSA or HSA money for 23andMe’s health offerings.
<h2>23andMe Services That Are FSA/HSA Eligible</h2>
The Internal Revenue Service also ruled in 2019 that the health portion of the cost of the 23andMe Health + Ancestry Service may be eligible. Customers can use our<a href="https://www.23andme.com/fsa-hsa-eligibility/calculator/"> FSA/HSA calculator </a>to determine how much is eligible. 
In 2021, 23andMe introduced the 23andMe Health Service which is FSA &amp; HSA eligible and includes health predisposition reports**, carrier status reports**, and wellness reports. The 23andMe Health Service is only available on the <a href="https://fsastore.com/23andme-health-only-service/32162.html">FSA/HSA store</a> and on <a href="https://www.amazon.com/23andMe-Health-Service-Including-Predispositions/dp/B09JFV4Z95?maas=maas_adg_9355566F4DC6DBE77B3FBD8B090C0C24_afap_abs&amp;ref_=aa_maas&amp;tag=maas">Amazon’s FSA/HSA store</a>. 
Now much more of 23andMe’s health offerings are eligible. For instance, the annual membership fees for <a href="https://www.23andme.com/membership/">23andMe+ Premium</a> and <a href="https://www.23andme.com/total-health/">23andMe+ Total Health</a> may be eligible for reimbursement based upon the IRS’s reasoning in their 2019 ruling. <a href="https://blog.23andme.com/articles/total-health/th-pdp-kit-1c9c1efa996d114d39464fcef61794cc" rel="attachment wp-att-32291"><img loading="lazy" decoding="async" class="size-full wp-image-32291 alignnone" src="http://35.88.189.111/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc.png" alt="" width="1176" height="966" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc.png 1176w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc-300x246.png 300w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc-768x631.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc-1024x841.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-pdp-kit.1c9c1efa996d114d39464fcef61794cc-880x723.png 880w" sizes="auto, (max-width: 1176px) 100vw, 1176px" /></a>
 
Customers can use money from these accounts to cover such things as clinical lab tests and clinician fees coordinated through 23andMe and may also be able to apply funds from their FSA or HSA accounts to upgrade to 23andMe&#8217;s Health + Ancestry Service, 23andMe+ Premium, or 23andMe+ Total Health, which are considered eligible expenses. In addition, the IRS allows customers to use FSA/HSA funds for a portion (up to $189†) of the cost of the <a href="https://www.23andme.com/dna-health-ancestry/">23andMe Health + Ancestry Service</a>.
<a href="https://blog.23andme.com/articles/23andme-now-available-in-uk-at-boots-online/ha-kit-med_2x-7e3f651f61e3" rel="attachment wp-att-26768"><img loading="lazy" decoding="async" class="size-full wp-image-26768 alignnone" src="http://35.88.189.111/wp-content/uploads/2018/12/ha-kit-med_2x.7e3f651f61e3.jpg" alt="" width="552" height="286" srcset="https://blogcms.23andme.com/wp-content/uploads/2018/12/ha-kit-med_2x.7e3f651f61e3.jpg 552w, https://blogcms.23andme.com/wp-content/uploads/2018/12/ha-kit-med_2x.7e3f651f61e3-300x155.jpg 300w" sizes="auto, (max-width: 552px) 100vw, 552px" /></a>
<h2>Learn More</h2>
If you are trying to determine what portion of your purchase, membership, or upgrade may be  eligible, the simplest way to figure out the likely eligible amounts would be to use our <a href="https://www.23andme.com/fsa-hsa-eligibility/calculator/">FSA/HSA calculator</a>. We also have more details on our <a href="https://www.23andme.com/fsa-hsa/">FSA/HSA page</a>. Additionally, you should always check with your specific FSA/HSA benefits coordinator and/or your tax professional for confirmation on the specific requirements for reimbursement, including eligibility, usage, procedures, and qualifications. To purchase the 23andMe Health Service visit <a href="https://fsastore.com/23andme-health-only-service/32162.html">the FSAStore</a>, or go to Amazon <a href="https://www.amazon.com/23andMe-Health-Service-Including-Predispositions/dp/B09JFV4Z95?maas=maas_adg_9355566F4DC6DBE77B3FBD8B090C0C24_afap_abs&amp;ref_=aa_maas&amp;tag=maas">here</a>. 
Still have questions? Here are answers to some of the most frequently asked questions about <a href="https://customercare.23andme.com/hc/en-us/articles/360026466094">FSA &amp; HSA eligibility and 23andMe.</a>
Learn about all 23andMe has to offer <a href="https://www.23andme.com/compare-dna-tests/?bst=pff">here</a>. 


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<h2>Note:</h2>
This material has been prepared for informational purposes only, and is not intended to provide, and should not be relied on for, tax, legal or accounting advice. 23andMe does not provide tax, legal, or accounting advice. You should consult your specific FSA/HSA benefits coordinator and/or your tax professional for further information regarding the application of the tax laws and confirmation on the specific requirements for reimbursement, including eligibility, usage, procedures, and qualifications. 
*Check with your specific FSA/HSA benefits coordinator and/or your tax professional for confirmation on the specific requirements for reimbursement, including eligibility, usage, procedures, and qualifications. 
**The 23andMe PGS test includes health predisposition and carrier status reports. 23andMe health predisposition reports include both reports that meet FDA requirements for genetic health risks and reports which are based on 23andMe research and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future, the health of your fetus, or your newborn child&#8217;s risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. For important information and limitations regarding each genetic health risk and carrier status report, visit 23andme.com/test-info/.
†Based on the purchase price of $229. Check with your FSA/HSA administrator and/or your tax professional for specific requirements for individual eligibility and reimbursement. 


<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="1024" height="1024" src="http://35.88.189.111/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-1024x1024.png" alt="" class="wp-image-29342" srcset="https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-1024x1024.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-150x150.png 150w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-300x300.png 300w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-768x768.png 768w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-880x880.png 880w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-1180x1180.png 1180w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-271x271.png 271w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-372x372.png 372w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-574x574.png 574w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit-980x980.png 980w, https://blogcms.23andme.com/wp-content/uploads/2021/11/Amazon-Thumbnail-HO-Kit.png 1500w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>

23andMe Blog

23andMe Blog Team

23andMe Health Offerings Are FSA & HSA Eligible

Good health depends on a good night’s rest, but in the wee hours, sleep eludes many of us; some estimates suggest that as many as<a href="https://pubmed.ncbi.nlm.nih.gov/28348990/"> 30 percent of adults</a> have insomnia, defined as an inability to fall asleep at least three times a week over several months.



Many factors, such as stress, certain medications, poor sleep hygiene, or alcohol or caffeine close to bedtime, can play a role in why some of us toss and turn each night. But genetics also influences our ability to sleep.



This week, 23andMe released a new Insomnia report (Powered by 23andMe Research) and available to 23andMe+ Premium members.



<h6 class="wp-block-heading" id="h-about-the-report">About the Report</h6>



The new 23andMe+ report on insomnia uses data from people who have consented to participate in 23andMe research. Leveraging this data, we use machine learning techniques to estimate an individual’s likelihood of developing insomnia.



The estimates factor in that data and use statistical modeling that includes thousands of genetic markers and information on an individual’s ethnicity and birth sex. Together, all this data is used to calculate the genetic likelihood of developing&nbsp; insomnia. Customers can learn more about the science and methodology behind our new report in this<a href="https://permalinks.23andme.com/pdf/23_21-PRSMethodology_May2020.pdf"> white paper</a>.



The report provides users with helpful information on their estimated genetic likelihood of developing insomnia, but it is not a substitute for clinical diagnosis or treatment.



<h6 class="wp-block-heading" id="h-what-is-insomnia">What is Insomnia?</h6>



All of us struggle to get to sleep occasionally, but insomnia causes persistent problems with not just falling asleep but staying asleep. Insomnia can last a few days or weeks, but when it lasts more than three months or more, it is considered chronic.



Beyond external factors like stress, diet, or medication, scientists are still trying to understand the genetics of insomnia fully.



<a href="https://blog.23andme.com/articles/genetics-of-insomnia-more-similar-to-psychiatric-conditions-than-to-other-sleep-traits">Insomnia</a> is highly polygenic, meaning many different genes are associated with the condition. Still, several studies have narrowed down on a combination of genetic factors that contribute to the disruption of the sleep-wake cycle or change the chemical cycles in the brain that control sleep. In 2022, 23andMe collaborated with researchers at Vrije University in Amsterdam that included data from more than 2.3 million individuals and identified<a href="https://blog.23andme.com/articles/insomnia-study"> 289 genetic variants associated with insomnia</a>.



The impact of sleep or the lack of sleep has been well studied. The more obvious symptoms are daytime drowsiness, low energy, and trouble concentrating or remembering things. Drowsiness itself contributes to other public safety issues, such as<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831237/"> car accidents</a>. But insomnia can also impact mental health. It’s associated with depression and anxiety, for instance. Long-term insomnia is also associated with health conditions such as high blood pressure, heart disease, and diabetes.&nbsp;



For people who have chronic insomnia, <a href="https://www.nhlbi.nih.gov/health/insomnia/treatment">treatment</a> with cognitive behavioral therapy and lifestyle modifications can help address the causes of insomnia. In extreme cases, doctors may recommend sleep-aid medications that can help too.



<h6 class="wp-block-heading" id="h-more-on-sleep">More on Sleep</h6>



Sleep allows our bodies and brains to shut down and rest. But there is more going on during sleep, especially during the various stages of sleep, each linked to different electrical patterns in our brains that all likely play an essential role in health.



There are two types of sleep — rapid eye movement or REM sleep and non-REM sleep. Non-REM sleep is often where we begin, and it is characterized by a slowing down of your heart rate and breathing but a period during which you are more easily awakened.&nbsp;



There are different stages of non-REM sleep, with each stage characterized by slower brain waves; the <a href="https://blog.23andme.com/articles/sleepy-time">deepest stage of non-REM sleep</a> includes periods with very low frequency waves, known as Delta waves, and is considered restorative.



You dream during REM sleep. The stage is characterized not just by rapid eye movement but also by rapid breathing and heart rate and blood pressure increases. Typically, a person enters REM sleep an hour or an hour after falling asleep, lasting about 10 minutes to an hour. After REM sleep, the process repeats. Typically, about a fifth of our sleep is REM sleep. 



Dreams and REM sleep help with learning and making memories. Other stages of sleep, for instance, are crucial for creating pathways for learning and remembering.



Researchers are still trying to understand why sleep is so essential. 23andMe scientists and their collaborators have looked at several components of sleep, including <a href="https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1006125">wake times</a>,<a href="https://research.23andme.com/wp-content/uploads/2018/10/Y_Huang_ASHG18_final.pdf"> sleep apnea,</a> and <a href="https://www.sciencedirect.com/science/article/abs/pii/S019745802030124X?via%3Dihub">REM sleep</a>.



<h6 class="wp-block-heading" id="h-more-23andme-reports-on-sleep">More 23andMe Reports on Sleep</h6>



23andMe also offers customers various sleep-related reports. Those include wellness reports on deep sleep, sleep movement, and 23andMe+ reports (Powered by 23andMe Research) on obstructive sleep apnea and restless leg syndrome. These different sleep-related issues could affect sleep patterns and contribute to restlessness.



In 2021, during the height of the COVID pandemic, 23andMe conducted <a href="https://blog.23andme.com/articles/covid-impact-on-sleep">a sleep survey</a>, which found that the pandemic had a profound impact on sleep. It was also consistent with other published studies during the period. Another<a href="https://nutrition.bmj.com/content/4/1/132"> study published in 2021</a> noted that sleep disruption and stress among healthcare workers during the pandemic were also associated with a higher risk of infection and more severe symptoms from COVID-19. However, broad population-wide changes in sleep patterns are relatively easy to study.&nbsp;



Along with the new 23andMe+ Insomnia report (Powered by 23andMe Research), 23andMe also has a collection of other sleep-related reports. Some are included in the 23andMe+ Premium membership, such as the Obstructive Sleep Apnea and the Restless Leg Syndrome reports (Powered by 23andMe Research). But 23andMe’s Health + Ancestry Service also includes sleep-related Wellness reports, including reports on Deep Sleep, Sleep Movement, and Wake-Up Time. Each is meant to look at how your genetics may play a role in the quality of your sleep.



<h6 class="wp-block-heading" id="h-find-out-more">Find Out More</h6>



23andMe+ Premium members can click<a href="https://you.23andme.com/reports/prs.insomnia/"> here</a> if they wish to view their report.



Current 23andMe Health + Ancestry Service customers on the current genotyping chip can receive this and 35+ other reports by joining a 23andMe+ Premium membership within their account. Learn more<a href="https://you.23andme.com/subscription/"> here</a>.



Not a 23andMe+ Premium member yet? Learn more about what 23andMe has to offer<a href="https://www.23andme.com/compare-dna-tests/"> here</a>.

New Genetic Report on Insomnia

Genetic counselors are an integral part of 23andMe, including a role in helping to shape many health related reports, features and services we offer. In honor of Genetic Counselor Awareness Day we’re highlighting their role at 23andMe and the important role genetic counselors play within healthcare more broadly.



<h6 class="wp-block-heading" id="h-what-do-genetic-counselors-do">What do genetic counselors do?</h6>



Genetic counselors have specialized training and education in both medical genetics and counseling. As their professional title suggests, genetic counselors lean upon their background training in counseling skills to help people looking for support to interpret and understand their test results.&nbsp;



We are proud to have six genetic counselors in various roles at 23andMe. While 23andMe genetic counselors do not provide individual genetic counseling services to our millions of customers, they work as a team to make access to genetic information possible on a large scale.&nbsp;



The work our <a href="https://medical.23andme.com/medical-team/">Genomic Health team</a> does is diverse and supports the various <a href="https://www.23andme.com/about/">values that guide our company</a>. Some of the team focuses on 23andMe reports, creating and updating the reports that bring clear and accurate genetic information to our customers. Others provide <a href="https://blog.23andme.com/articles/genetic-report-consults?gad_source=1&amp;gclid=CjwKCAjwkY2qBhBDEiwAoQXK5aNWLlLpQjqDFuNEYPMnweywhEC0ChSUHWpa094p9AJ3BXJwIPx9WRoCyIYQAvD_BwE&amp;gclsrc=aw.ds">genetics education through learning programs for clinicians</a>, <a href="https://medical.23andme.com/pharmacogenetics-video/">informational videos</a> on genetics, and <a href="https://perspectives.nsgc.org/Article/busting-common-misconceptions-about-direct-to-consumer-genetic-testing">articles and other communications for healthcare professionals</a>.&nbsp;



<h6 class="wp-block-heading" id="h-who-are-the-genetic-counselors-at-23andme-nbsp-nbsp">Who are the genetic counselors at 23andMe?&nbsp;&nbsp;</h6>



<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="683" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Stacey-headshot-BW-683x1024.jpg" alt="" class="wp-image-32327" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-683x1024.jpg 683w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-587x880.jpg 587w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-787x1180.jpg 787w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-768x1152.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Stacey-headshot-BW-scaled.jpg 1706w" sizes="auto, (max-width: 683px) 100vw, 683px" /><figcaption class="wp-element-caption">Stacey Detweiler, MS, LCGC &#8211; Medical Affairs Manager</figcaption></figure>



“Making genetics accessible and paving a path towards precision medicine is an honor and a joy.”&nbsp;



Stacey joined 23andMe in 2016 as a Medical Affairs Associate and focuses on product, clinical, and educational development. She ensures our product and marketing include consumer-friendly information that’s medically accurate.



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<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="682" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-682x1024.jpg" alt="" class="wp-image-32326" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-682x1024.jpg 682w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-768x1153.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-586x880.jpg 586w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-786x1180.jpg 786w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Anne-Greb-headshot-in-black-and-white-scaled.jpg 1706w" sizes="auto, (max-width: 682px) 100vw, 682px" /><figcaption class="wp-element-caption">Anne Greb, MS, CGC, 23andMe Lead, Medical Education</figcaption></figure>



“For the past three decades, I eagerly anticipated this new era of precision and genomic medicine.”



Anne joined 23andMe in 2018 and leads our Medical Education Team. She specializes in educating clinicians on how to answer questions from patients about their 23andMe reports.&nbsp;



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<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="682" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Marlena-headshot-BW-682x1024.jpg" alt="" class="wp-image-32330" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-682x1024.jpg 682w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-768x1152.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-586x880.jpg 586w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-786x1180.jpg 786w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Marlena-headshot-BW-scaled.jpg 1706w" sizes="auto, (max-width: 682px) 100vw, 682px" /><figcaption class="wp-element-caption">Marlena Orthlieb, MGCS, LCGC &#8211; Medical Affairs Associate</figcaption></figure>



“I am thrilled that we are building unprecedented opportunities for people to access and benefit from their genome.”



Marlena joined 23andMe as a Medical Affairs Associate in 2022. Her roles are varied at 23andMe, from communication and research efforts to product and service development.&nbsp;



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<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="682" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-682x1024.jpg" alt="" class="wp-image-32329" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-682x1024.jpg 682w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-768x1153.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-586x880.jpg 586w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-786x1180.jpg 786w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Amy-Sturm-headshot-in-BW-scaled.jpg 1706w" sizes="auto, (max-width: 682px) 100vw, 682px" /><figcaption class="wp-element-caption"> Amy Sturm, MS, CGC &#8211; Director of Population Health Genomics</figcaption></figure>



“I’m thrilled to help build a path for individuals on their health journey.”&nbsp;



Amy joined the 23andMe team in 2022 and is Director of Population Health Genomics at 23andMe. She provides expertise and strategic guidance across many teams at 23andMe as the company seeks to evolve and scale its health-related products and services.



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<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="683" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Hannah-headshot-in-BW-683x1024.jpg" alt="" class="wp-image-32332" style="aspect-ratio:1;object-fit:cover" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-683x1024.jpg 683w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-587x880.jpg 587w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-787x1180.jpg 787w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-768x1152.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Hannah-headshot-in-BW-scaled.jpg 1706w" sizes="auto, (max-width: 683px) 100vw, 683px" /><figcaption class="wp-element-caption"> Hannah Llorin, MS, LCGC &#8211; Genetic Counselor</figcaption></figure>



“I am privileged to be helping people benefit from their genetic information while integrating principles of diversity, equity and inclusivity.”



Hannah (she/her) joined 23andMe in 2023. She works to develop clinical support tools and educational resources for healthcare professionals and interacts closely with the medical team that delivers genetics-informed clinical services through the 23andMe and Lemonaid Health platforms.&nbsp;



<hr class="wp-block-separator has-alpha-channel-opacity"/>



<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="683" height="1024" src="http://35.88.189.111/wp-content/uploads/2023/11/Brianne-headshot-in-BW-683x1024.jpg" alt="" class="wp-image-32331" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-683x1024.jpg 683w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-200x300.jpg 200w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-768x1151.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-587x880.jpg 587w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-787x1180.jpg 787w, https://blogcms.23andme.com/wp-content/uploads/2023/11/Brianne-headshot-in-BW-scaled.jpg 1708w" sizes="auto, (max-width: 683px) 100vw, 683px" /><figcaption class="wp-element-caption"> Brianne Kirkpatrick, MS, LCGC &#8211; Medical Communications Manager</figcaption></figure>



“Being a genetic counselor is not a job; it’s a way of approaching genetic information with appreciation, and respect.”



Brianne joined the Genomic Health team in 2023 as Medical Communications Manager. She leads the Genomic Health team’s communications within the company and externally with the network of providers who participate in 23andMe for Healthcare Professionals.&nbsp;



<h6 class="wp-block-heading" id="h-why-would-i-need-to-go-to-a-genetic-counselor-nbsp">Why would I need to go to a genetic counselor?&nbsp;</h6>



There are several reasons you might benefit from meeting with a genetic counselor or other healthcare professional with training in genetics–if you’re seeking to better understand a test result, for example, or have a known genetic condition in your family. You might also meet with a genetic counselor if you are planning to start a family and are concerned about an inherited condition or are working with a fertility specialist and considering genetic testing as part of the process.&nbsp;



Here are a few more reasons: If you have a family history of cancer, Alzheimer’s disease, a heart disorder, or another genetic condition, a genetic counselor may help you better understand what that specific history might mean for your own risks or for others in your family. Some people seek out genetic counseling after having a genetic test and learning that they have a genetic variant that puts them at a higher risk for a condition.&nbsp;



In all of these cases, genetic counselors can help you explore what the next steps might be for you and your family.&nbsp;



<h6 class="wp-block-heading" id="h-where-can-i-find-a-genetic-counselor-to-work-with-individually">Where can I find a genetic counselor to work with individually?</h6>



There are several resources out there for you if you might be considering or interested in working with a genetic counselor one-on-one. Our post on <a href="https://blog.23andme.com/health-traits/report-for-healthcare-provider/">sharing your 23andMe report with your healthcare provider</a> helps 23andMe customers get started on the path. Customers may also work with a clinician that delivers genetics-informed services through the 23andMe and Lemonaid Health platforms. This is a group of healthcare professionals who have received specific training to answer questions about a growing number of 23andMe reports.&nbsp;&nbsp;



Another option is to search the <a href="https://www.findageneticcounselor.com/">Find A Genetic Counselor</a> tool developed by the National Society of Genetic Counselors. There is also a directory of genetic counselors on the <a href="https://abgc.learningbuilder.com/Search/Public/MemberRole/Verification">American Board of Genetic Counseling</a> site. Finally, your doctor or other healthcare professional can assist in making a referral to a genetic counselor in your area.

Genetic Counselor Awareness Day 2023

This week, 23andMe launched Health Action Plan, a new digital feature that combines genetic data, health history, and biomarkers from bloodwork to offer personalized recommendations for better health for 23andMe+ Premium members.



<figure class="wp-block-image alignright size-full is-resized"><img loading="lazy" decoding="async" width="786" height="1704" src="http://35.88.189.111/wp-content/uploads/2023/09/Action-plan-4.png" alt="An image of the mobile version of the Health Action Plan recommendations page." class="wp-image-32204" style="width:360px;height:undefinedpx" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4.png 786w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4-138x300.png 138w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4-768x1665.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4-472x1024.png 472w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4-406x880.png 406w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-4-544x1180.png 544w" sizes="auto, (max-width: 786px) 100vw, 786px" /></figure>



<h6 class="wp-block-heading" id="h-tailored-recommendations">Tailored Recommendations</h6>



Health Action Plan can help customers take the next step for prevention, early detection of risk, and give people a path forward in their health journey. It offers customers personalized, specific actions and next steps. 23andMe created this new feature partly because many of our customers said they wanted help prioritizing what steps they should focus on to mitigate risk and optimize their health.



“We frequently hear from customers that they want to take action based on their genetic health information but don&#8217;t know where to start,” said Robin Smith, Ph.D., Director of 23andMe Product Management. “Health Action Plan provides them with a prioritized to-do list of recommendations based on their DNA or other self-reported health history that&#8217;s updated as new reports are released or as the science changes.”



The personalized recommendations from Health Action Plan are based on U.S. guidelines, and will help 23andMe+ Premium members focus on what’s most important for their health, and then give them actionable steps they can take to help improve their own health journey.



<h6 class="wp-block-heading" id="h-more-than-just-genetics">More than Just Genetics</h6>



This new feature is like a genetic check-up, but it includes much more than DNA data.



With a customer’s consent, Health Action Plan draws on genetic health reports as well as a person’s self-reported health history and blood test results. Together, this data helps inform tailored recommendations, prioritizing what are the most important steps for a customer to take. As customers answer health survey questions, 23andMe will be able to expand the breadth of recommendations made to customers, offering further insights on actions they should take next.



Health Action Plan also works in tandem with the other features such as the self reported health history and or answers to survey questions as well as features such as <a href="https://blog.23andme.com/articles/stay-on-track-with-23andme-health-tracks">Health Tracks</a>SM.



<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="1024" height="719" src="http://35.88.189.111/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-1024x719.png" alt="An image of the mobile display for health tracks looking at different trajectories of risk based on genetics, and a healthy lifestyle." class="wp-image-32105" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-1024x719.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-300x211.png 300w, https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-768x539.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-880x618.png 880w, https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM-1180x828.png 1180w, https://blogcms.23andme.com/wp-content/uploads/2023/08/Screenshot-2023-08-16-at-3.48.27-PM.png 1732w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>



Health Tracks uses data visualization to allow 23andMe+ Premium members see how making healthy changes, including taking steps recommended through Health Action Plan, could significantly bend the risk curve over time and steer them toward healthier outcomes, even for those with a higher genetic likelihood of developing one of those conditions.



<h6 class="wp-block-heading" id="h-recommendations">Recommendations</h6>



Health Action Plan might include recommendations around diet, or reducing stress, improving sleep, or other lifestyle changes. But based on genetics in combination with non-genetic risk factors, Health Action Plan may also help identify the need for a customer to talk to a doctor or for more clinical services.



So, for example, if an individual’s&nbsp; genetic health predisposition is an&nbsp; increased likelihood for developing high triglycerides, a recommendation might be to get a blood test that looks at triglycerides and other lipids. This is important because while high triglycerides often have no symptoms, they can be a risk factor not just for heart disease but can be part of something called<a href="https://www.nhlbi.nih.gov/health/metabolic-syndrome"> metabolic syndrome</a>. Metabolic syndromes increase the risk for serious conditions like heart disease, stroke, and type 2 diabetes.



For individuals with an increased likelihood for developing high triglycerides or who do currently have high triglycerides or other lipids, there are steps one can take including changes in diet and lifestyle that could help.



<figure class="wp-block-image alignright size-full is-resized"><img loading="lazy" decoding="async" width="236" height="512" src="http://35.88.189.111/wp-content/uploads/2023/09/Action-plan-3.png" alt="An image of the Health Action Plan recommendations." class="wp-image-32205" style="width:360px;height:undefinedpx" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-3.png 236w, https://blogcms.23andme.com/wp-content/uploads/2023/09/Action-plan-3-138x300.png 138w" sizes="auto, (max-width: 236px) 100vw, 236px" /></figure>



<h6 class="wp-block-heading" id="h-23andme-and-blood-testing-nbsp">23andMe and Blood Testing &nbsp;</h6>



Eligible <a href="https://www.23andme.com/membership/">23andMe+ Premium</a> members may have the ability to have a healthcare provider order a lab test, and return results with a clinical analysis through the 23andMe experience.* 



A clinician ordered lab test can be done through the 23andMe experience and is both intuitive and simple. The test itself will be done at a local lab. Once the results are completed, customers will be able to not just view their results, but also have the opportunity to get a clinical analysis of your results from a Lemonaid Health clinician — Lemonaid Health is a telemedicine company owned by 23andMe. In addition, by adding this kind of bloodwork and biomarker data, customers can receive additional tailored recommendations that can be even further prioritized and continue to help identify potential health risks.&nbsp;



While the new Health Action Plan might suggest getting additional lab tests or consulting with a healthcare provider, customers will also get lifestyle recommendations about things like diet and exercise.



If a customer wishes they can also dismiss or silent certain recommendations.



It’s important to note that none of the recommendations should be used to replace a visit to a primary care physician.



<h6 class="wp-block-heading" id="h-find-out-more">Find Out More</h6>



This initial release of Health Action Plan is part of 23andMe’s continued push to create genetically informed care for our customers. It aligns with our mission of empowering our customers by helping them access, understand, and benefit from the human genome.



This is just another addition to features and tools our customers can use to be more proactive about their health.&nbsp;



<a href="https://www.23andme.com/membership/">23andMe+ </a>Premium members can find the Health Action Plan feature under Health &amp; Traits or go<a href="https://you.23andme.com/health/healthactionplan/"> here</a>.



Not yet a 23andMe+ Premium member? Find out more all that 23andMe has to offer and<a href="https://www.23andme.com/compare-dna-tests/"> compare our services here</a>.



<hr class="wp-block-separator has-alpha-channel-opacity"/>



*Blood testing through 23andMe is not available in NY, NJ, RI, OK, HI, PR

An illustration showing families exercising.

A Health Action Plan for You

Today, 23andMe is announcing its new, advanced health membership – <a href="https://www.23andme.com/total-health/">23andMe+ Total Health</a>™, which launches to new consumers in early November.&nbsp;



Total Health is designed to be a comprehensive, prevention-based membership, combining clinical grade exome sequencing, biannual blood testing, and unprecedented access to clinicians trained in genetics. Total Health will also include all the reports and features offered in our existing <a href="https://www.23andme.com/membership/">23andMe+ Premium Membership</a> in addition to these new services.&nbsp;



<figure class="wp-block-image aligncenter size-large"><img loading="lazy" decoding="async" width="1024" height="640" src="http://35.88.189.111/wp-content/uploads/2023/10/23andme-plus-total-health-1024x640.png" alt="" class="wp-image-32474" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/23andme-plus-total-health-1024x640.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/10/23andme-plus-total-health-300x187.png 300w, https://blogcms.23andme.com/wp-content/uploads/2023/10/23andme-plus-total-health-768x480.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/10/23andme-plus-total-health-880x550.png 880w, https://blogcms.23andme.com/wp-content/uploads/2023/10/23andme-plus-total-health-1180x737.png 1180w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>



“We’re bringing the power of genetics into your personal healthcare journey,” said 23andMe’s Vice President of Genomic Health Noura Abul-Husn, M.D. Ph.D. “We’re offering comprehensive genetic testing – including exome sequencing – to help you understand your disease risks, blood testing to check on your health status, and access to clinicians with unique expertise to guide your next steps.”



As a medical geneticist Noura said she wants people to understand how their genetic information is connected to their health. This empowers them to use&nbsp;that knowledge to stay healthy, she said.



“We don’t typically see genetics being used this way in healthcare, but it can, and it should. It’s about prevention,” Noura said. “It’s personal. It’s the whole story. It’s Total Health.”



<h2 class="wp-block-heading" id="h-a-prevention-focused-future">A prevention-focused future</h2>



Total Health delivers on our mission to help people access, understand and benefit from the human genome. This membership is for individuals who want to augment their current healthcare experience with even more direct access to comprehensive genetic testing, risk assessment in critical health areas, and personalized health plans driven by clinicians with unique knowledge and training in genetics. This is for the consumer who is actively focused on ongoing health management, longevity and direct access to even more testing so they can mitigate, or prevent, disease.



Through the combination of critical health data, including comprehensive and personalized genetic information, blood biomarkers and personal and family medical history, the genetics-trained clinicians can provide risk assessments and help build a highly personalized, preventive health plan.



<figure class="wp-block-image aligncenter size-full"><img loading="lazy" decoding="async" width="639" height="279" src="http://35.88.189.111/wp-content/uploads/2023/10/Total-Health-Summary.jpg" alt="An image showing some of what is included in Total Health, exome sequening, bloodd tests, consult with clinician." class="wp-image-32293" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/Total-Health-Summary.jpg 639w, https://blogcms.23andme.com/wp-content/uploads/2023/10/Total-Health-Summary-300x131.jpg 300w" sizes="auto, (max-width: 639px) 100vw, 639px" /></figure>



<h2 class="wp-block-heading" id="h-what-s-included">What’s included?</h2>



Exome sequencing



Through advanced exome sequencing, members will receive clinician-ordered genetic testing that looks deeper into high impact genes associated with 55+ health conditions that, if detected early, may have effective preventive measures and clinical interventions. This includes screens for clinically actionable and under-diagnosed hereditary conditions related to cancer, cardiovascular, metabolic, kidney, neurological and other health conditions. This includes all <a href="https://www.ncbi.nlm.nih.gov/clinvar/docs/acmg/">genes considered medically actionable</a> by the American College of Medical Genetics (ACMG).&nbsp;



Biannual blood testing



<figure class="wp-block-image aligncenter size-full"><img loading="lazy" decoding="async" width="1176" height="966" src="http://35.88.189.111/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c.png" alt="What's included labs, consult and exome sequencing." class="wp-image-32290" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c.png 1176w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c-300x246.png 300w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c-768x631.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c-1024x841.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/10/th-desktop.42775e8b272a0a7941b83aa48d04d95c-880x723.png 880w" sizes="auto, (max-width: 1176px) 100vw, 1176px" /></figure>



While genetics offers insight into the future, blood testing gives insight into the now. Total Health members will get comprehensive blood tests that assess 55+ biomarkers, including ones that go beyond your routine labs. This includes measuring things like blood sugar levels, kidney, liver and thyroid function, along with cholesterol and advanced lipoprotein levels, which offer ongoing insight for prevention and early detection. Members will receive biannual testing, allowing them to track results and measure progress all within their 23andMe account. Blood testing is initiated by a clinician and members will complete their testing through a local lab offered by a third-party provider.&nbsp;



Access to clinicians trained in genetics



Total Health members will have access to clinicians trained in genetics. Clinicians will review all blood biomarkers, genetic data and personal and family medical history to provide members with personalized risk assessments and help build a preventive health plan tailored to each individual. Members are able to engage in an annual virtual clinician consultation, as well as have ongoing messaging conversations with clinicians about their reports, progress they are making, or to ask questions.



23andMe+ Premium Membership



As part of Total Health, members will gain access to all the premium reports and features delivered through <a href="https://www.23andme.com/membership/">23andMe+ Premium</a>. This includes:



<ul class="wp-block-list">
<li>FDA authorized reports offered through our Health + Ancestry Service*</li>



<li>Polygenic reports (powered by 23andMe research), which look at your genetic likelihood for more common conditions like high LDL cholesterol, asthma and anxiety</li>



<li>Pharmacogenetic reports, which help you understand how your genetics can impact how you process certain medications**</li>



<li>Enhanced ancestry features</li>
</ul>



<h2 class="wp-block-heading" id="h-expanding-coverage">Expanding coverage</h2>



Historically, 23andMe has offered reports using genotyping technology, a powerful, efficient and accurate way to examine DNA variants at certain pre-identified positions in the genome. The specific positions we look at are known to more commonly vary between individuals that span the entire genome.&nbsp;



However, exome sequencing is an advanced, comprehensive genetic testing technology that involves reading every DNA letter in its correct order within a given piece of the genome. This provides individuals with a more complete picture, surfacing the majority of genetic variants known to be associated with disease risk.



For example, we use genotyping for our BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report*, which looks at 44 variants within the BRCA1 and BRCA2 genes associated with breast, ovarian, and prostate cancer. With exome sequencing, Total Health will include reports that look at all the thousands of variants within the coding region of the BRCA1 and BRCA2 genes. We’ll also include thousands of variants in many other genes associated with increased cancer risks.&nbsp;



Our exome sequencing will go beyond cancer to also include clinical interpretations of high impact genes associated with other hereditary health conditions that, if detected early, may have effective prevention measures and clinical interventions.&nbsp;&nbsp;&nbsp;



<a href="https://www.23andme.com/total-health/">23andMe+ Total Health</a> offers members a fuller picture of their risk for disease, helping them navigate to a healthier future.&nbsp;



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<h6 class="wp-block-heading" id="h-availability-and-eligibility">Availability and Eligibility</h6>



Total Health is available for those 18 and older in the United States (excluding Hawaii, New Jersey, New York, and Rhode Island). The 23andMe+ Total Health membership costs $999, with an annual membership renewal of $499 per year.



Learn more about <a href="https://www.23andme.com/total-health/">23andMe+ Total Health™ here</a>.



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<h6 class="wp-block-heading" id="h-important-pgs-test-information">Important PGS Test Information</h6>



*The 23andMe PGS test includes health predisposition and carrier status reports. Health predisposition reports include both reports that meet FDA requirements for genetic health risks and reports which are based on 23andMe research and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future, the health of your fetus, or your newborn child&#8217;s risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk.&nbsp;



<h6 class="wp-block-heading" id="h-warnings-amp-limitations-nbsp">Warnings &amp; Limitations:&nbsp;</h6>



The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of 44 variants in the BRCA1 and BRCA2 genes. The report describes if a person&#8217;s genetic result is associated with an increased risk of developing breast cancer and ovarian cancer and may be associated with an increased risk for prostate cancer, pancreatic cancer, and potentially other cancers. The variants included in this report do not represent the majority of the BRCA1/BRCA2 variants in people of most ethnicities. This report does not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. This report is for over-the-counter use by adults over the age of 18, and provides genetic information to inform discussions with a healthcare professional. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. For important information and limitations regarding each genetic health risk and carrier status report, visit 23andme.com/test-info.



**23andMe PGS Pharmacogenetics reports: The 23andMe test uses qualitative genotyping to detect 3 variants in the CYP2C19 gene, 2 variants in the DPYD gene and 1 variant in the SLCO1B1 gene in the genomic DNA of adults from saliva for the purpose of reporting and interpreting information about the processing of certain therapeutics to inform discussions with a healthcare professional. It does not describe if a person will or will not respond to a particular therapeutic. Our CYP2C19 Pharmacogenetics report provides certain information about variants associated with metabolism of some therapeutics and provides interpretive drug information regarding the potential effect of citalopram and clopidogrel therapy. Our SLCO1B1 Pharmacogenetics report provides certain information about variants associated with the processing of some therapeutics and provides interpretive drug information regarding the potential effect of simvastatin therapy. Our DPYD Pharmacogenetics report does not describe the association between detected variants and any specific therapeutic. Results for DPYD and certain CYP2C19 results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. Warning: Test information should not be used to start, stop, or change any course of treatment and does not test for all possible variants that may affect metabolism or protein function. The PGS test is not a substitute for visits to a healthcare professional. Making changes to your current regimen can lead to harmful side effects or reduced intended benefits of your medication, therefore consult with your healthcare professional before taking any medical action. For important information and limitations regarding Pharmacogenetic reports, visit 23andme.com/test-info/pharmacogenetics.

A Totally New 23andMe Health Membership: Total Health

Sarah opened her 23andMe report and immediately understood that this was serious.



“I knew it was something I had to take action about right away, and that’s what I did,” she said.



<h6 class="wp-block-heading" id="h-on-a-whim">On a Whim</h6>



The Bay Area mother of two young children with a thriving career in tech, said she isn’t really sure what prompted her to buy a 23andMe kit for herself and her husband.



“I’m not an overly &#8216;woo woo&#8217; person, but I can’t explain it,” she said. “I knew about 23andMe, and that it was popular, but I can’t explain exactly why I felt so strongly about ordering it.”



<figure class="wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio"><div class="wp-block-embed__wrapper">
<iframe loading="lazy" title="Sarah&#039;s 23andMe Story" width="500" height="281" src="https://www.youtube.com/embed/IckIRlh406U?feature=oembed" frameborder="0" allow="accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share" referrerpolicy="strict-origin-when-cross-origin" allowfullscreen></iframe>
</div></figure>



It’s lucky she did.



<h6 class="wp-block-heading" id="h-brca1-brca2-selected-variants-genetic-health-risk-report">BRCA1/BRCA2 (Selected Variants) Genetic Health Risk Report</h6>



Of course, Sarah was curious about what she’d learn from exploring her DNA, but she didn’t go into the experience looking for a specific insight. She just felt she needed to order it, so she did. The kits arrived in the mail and she and her husband sent off their samples to the lab. A couple of weeks later she got a message in the 23andMe app letting her know her reports were in.



She opted in to view her Health reports, went through a short tutorial then opened her BRCA1/BRCA2 (Selected Variants) Genetic Health Risk Report.*



Right away, Sarah saw the test detected a variant in the BRCA2 gene that put her at higher risk for breast and ovarian cancer. She was stunned. Cancer didn’t run in her family, or at least not that she knew. Her paternal grandparents, both Holocaust survivors, lived long, healthy lives. And she was both fit and healthy herself.



“I knew it wasn’t good,” Sarah said.



<h6 class="wp-block-heading" id="h-this-is-serious">This is Serious</h6>



We’re sharing Sarah’s story as part of Breast Cancer Awareness Month. Throughout the month of October we’ll be highlighting how 23andMe has helped flagged a risk for those who might not have otherwise learned that they carried a risk variant. Indeed, most people with a BRCA1 or BRCA2 risk variant don’t know they have one, according to a 2018 study by researchers at <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324494/">Geisinger Health in Pennsylvania</a>.&nbsp;



Like many others, Sarah had no idea she had a risk variant until after she received her 23andMe report. But she’d opened her report just an hour before a birthday party in her honor, so she waited to process the newly received information. About a week later, at the end of an already scheduled annual physical with her general practitioner, she showed her doctor her 23andMe report.



“He said it was serious and told me he was referring me to the Hereditary Cancer Clinic at UCSF,” Sarah said.



<h6 class="wp-block-heading" id="h-taking-action">Taking Action</h6>



In quick succession, she saw a genetic counselor, was tested at the clinic to confirm that she did indeed carry the variant 23andMe detected, and began meeting with BRCA specialists. Their first recommendation was that she preventatively remove her fallopian tubes and ovaries to completely avoid future cancer risk to those organs. She acted fast, but after that first surgery she wasn’t yet ready for a preventative mastectomy, and instead elected to get a mammogram and MRI twice a year as part of a high risk breast cancer screening protocol, one that she wouldn’t have qualified for without her recent BRCA discovery given her cancer-free family history. But in November of 2022, about a year after first testing with 23andMe, her MRI came back abnormal. A biopsy showed that she had early-stage breast cancer in both breasts.



“I was shocked, but I went into action mode,” Sarah said.&nbsp;



<h6 class="wp-block-heading" id="h-knowledge-is-power">Knowledge is Power</h6>



Her doctors recommended she have a double mastectomy, and Sarah agreed and acted quickly. A month later she had surgery including the removal of lymph nodes on each side to test for the spread of any cancer cells outside her breast tissue. When the pathology on her removed breast tissue and nodes came back, Sarah received great news: her lymph nodes were clear and the cancer hadn’t spread. Her bilateral breast cancers had both been extremely small and caught incredibly early. As a result, Sarah didn’t need any post-surgical chemotherapy or radiation, and less than a year since her cancer diagnosis she is back to living her normal, vibrant life.



Sarah said that because of the size and type of cancers, its likely they wouldn’t have been discovered by a regular annual mammogram for many years.Thankfully, due to her high risk status as a BRCA carrier, she was able to get regular MRI’s which lead to early detection. Sarah believes that if she hadn&#8217;t&nbsp; gotten tested through 23andMe, she might not have discovered the cancers until many years later, and by then it may have been too late to successfully treat.



“I really believe 23andMe saved my life,” said Sarah. “If I never received that information I don’t know if I’d be sitting here in a couple of years…knowledge is power and whatever you learn you can act on … so empower yourself and take the test.”



23andMe’s BRCA1/BRCA2 (Selected Variants) Genetic Health Risk Report originally looked at three variants in those genes that are most common in people of Ashkenazi Jewish descent. In August, 23andMe received FDA authorization to add another 41 variants to its report.** Now the report looks at 44 variants. Many of these additional variants are most common in people with African American, Latino, or Asian ancestry. More than 20,000 23andMe customers have one of the variants that will be included in the updated report.



<figure class="wp-block-image size-full"><img loading="lazy" decoding="async" width="930" height="760" src="http://35.88.189.111/wp-content/uploads/2023/10/BRCA-2.0-Mobile.jpg" alt="" class="wp-image-32247" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile.jpg 930w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-300x245.jpg 300w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-768x628.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-880x719.jpg 880w" sizes="auto, (max-width: 930px) 100vw, 930px" /><figcaption class="wp-element-caption">23andMe recently added 41 additional variants to its BRCA1/BRCA2 (Selected Variants) report.</figcaption></figure>



<a href="https://www.23andme.com/dna-health-ancestry/">23andMe Health + Ancestry Service</a> customers tested on our latest genotyping chip have access to the expanded report.&nbsp;



Existing customers can view<a href="https://you.23andme.com/reports/ghr.brca_v2/"> their report here</a>. Not yet a customer? You can find out<a href="https://www.23andme.com/compare-dna-tests/"> all that 23andMe has to offer here</a>.



<hr class="wp-block-separator has-alpha-channel-opacity"/>



<h6 class="wp-block-heading" id="h-important-test-information">Important Test Information:</h6>



The 23andMe PGS test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks, including the 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants). Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. The test is not intended to diagnose any disease and does not describe a person’s overall risk of developing any type of cancer. It is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatments. 



<h6 class="wp-block-heading" id="h-warnings-amp-limitations">Warnings &amp; Limitations: </h6>



The 23andMe PGS Genetic Health RIsk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of the 185delAG and 5382insC variants in the BRCA1 gene and the 6174delT variant in the BRCA2 gene. The report describes if a woman is at increased risk of developing breast and ovarian cancer, and if a man is at increased risk of developing breast cancer or may be at increased risk of developing prostate cancer.&nbsp; The three variants included in this report are most common in people of Ashkenazi Jewish descent and do not represent the majority of BRCA1/BRCA2 variants in the general population. This report does not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed in a clinical setting before taking any medical action.



<h6 class="wp-block-heading" id="h-important-test-information-for-updated-report">Important Test Information for Updated Report:</h6>



**The 23andMe PGS test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks, including the 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants). Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. The test is not intended to diagnose any disease and does not describe a person&#8217;s overall risk of developing any type of cancer. It is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatments. 



<h6 class="wp-block-heading" id="h-warnings-amp-limitations-0">Warnings &amp; Limitations: </h6>



The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of 44 variants in the BRCA1 and BRCA2 genes. The report describes if a person&#8217;s genetic result is associated with an increased risk of developing breast cancer and ovarian cancer and may be associated with an increased risk for prostate cancer, pancreatic cancer, and potentially other cancers. The variants included in this report do not represent the majority of the BRCA1/BRCA2 variants in people of most ethnicities. This report does not include variants in other genes linked to hereditary cancers and the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. This report is for over-the-counter use by adults over the age of 18, and provides genetic information to inform discussions with a healthcare professional. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action.

A photo of Sara at home with her daughter.

Sarah’s 23andMe Report Leads to Preventative Action

Expands Coverage for Underrepresented Populations



<figure class="wp-block-image aligncenter size-full"><img loading="lazy" decoding="async" width="930" height="760" src="http://35.88.189.111/wp-content/uploads/2023/10/BRCA-2.0-Mobile.jpg" alt="" class="wp-image-32247" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile.jpg 930w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-300x245.jpg 300w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-768x628.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/10/BRCA-2.0-Mobile-880x719.jpg 880w" sizes="auto, (max-width: 930px) 100vw, 930px" /></figure>



As we recognize Breast Cancer Awareness Month, 23andMe is also releasing its expanded BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report,* adding 41 additional variants to the report. Many of these variants are more common in people of African American, Hispanic/Latino, and Asian descent.



All of these variants are associated with a higher likelihood of breast, ovarian, prostate, and pancreatic cancer, no matter your ancestry. This new addition builds upon 23andMe’s original BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report, which in 2018 received the first-ever FDA authorization for a direct-to-consumer genetic health risk test for cancer. The original report provided information on three BRCA1/2 variants, most prevalent in those with Ashkenazi Jewish ancestry.



<h6 class="wp-block-heading" id="h-addressing-health-disparities-in-cancer-risk-detection">Addressing Health Disparities in Cancer Risk Detection</h6>



Adding additional variants to the BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report will expand the number of people benefitting from the report. Studies have found that <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324494/">more than 80 percent</a> of people with a BRCA1 or BRCA2 risk variant don’t know they have it. Many do not have a family history of cancer that would qualify them for traditional genetic testing through a healthcare professional. Layered onto that are disparities in access to BRCA1/2 genetic testing in some communities in the U.S., including the Black, Hispanic/Latino, and Asian communities. Black Americans also experience <a href="https://pubmed.ncbi.nlm.nih.gov/36190501/">dramatic disparities in breast cancer outcomes</a>, according to published research by the American Cancer Society.&nbsp;



“While the incidence of breast cancer is higher in white women, Black women are more likely to die of breast cancer,” said Vina Morris, a two-time breast cancer survivor and founder of the breast cancer awareness organization AfroPink. “This startling health disparity may be explained through lack of access to quality healthcare and delayed screening, which prevents earlier detection and more promising treatment options.”



<a href="https://afropink.org/who-we-are/">AfroPink</a> is a non-profit breast cancer awareness organization that focuses on dispelling myths about the disease within the Afro-American community. The group also provides resources and encourages prevention.



<h6 class="wp-block-heading" id="h-more-coverage-helping-more-people">More Coverage Helping More People</h6>



Vina attended a recent Breast Cancer Awareness Month event in New York City. She was there with 23andMe’s Vice President of Genomic Health, Noura Abul-Husn, MD, PhD. Noura highlighted the expanded coverage of 23andMe’s BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report. Noura noted that more than 20,000 23andMe customers — including both female and male customers — have one of the risk variants included in the updated report.&nbsp;



The 44 genetic variants included in the report account for about 30-to-40 percent of cancer-related BRCA variants among people of African American, non-Ashkenazi European, and Hispanic/Latino descent. The added variants also include several in people of East Asian and South Asian descent. Thousands of variants within the BRCA1 and BRCA2 genes confer an increased risk for cancer. While this report includes some more common variants, it does not include all BRCA risk variants. Knowing one has a variant offers customers a chance to discuss options with their healthcare provider. This might involve getting confirmatory genetic testing or taking preventive action. They may also include enhanced surveillance of prophylactic surgery or medication. 



<h6 class="wp-block-heading" id="h-availability">Availability</h6>



The expanded report is available to existing 23andMe Health + Ancestry Service customers who were genotyped on 23andMe’s <a href="https://customercare.23andme.com/hc/en-us/articles/218392668-Upgrading-to-23andMe-s-Newest-Chip-Version">latest genotyping chip</a>, V5. As with select other Genetic Health Risk reports*, customers must specifically opt-in if they want to view the the report. The report also includes an education module. This ensures customers are thoroughly informed on what they can learn, the report&#8217;s limitations, and how to use the results.



The 23andMe BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report utilizes the same informational concepts previously demonstrated in studies submitted to the FDA for its Genetic Health Risk reports. Those were shown to have 90 percent or greater overall user comprehension in a demographically diverse population study.&nbsp;



23andMe also carried out robust analytical validation studies to <a href="https://blog.23andme.com/articles/brca1-brca2">meet FDA requirements</a>. This allowed 23andMe to add variants to the BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report. Each variant tested demonstrated &gt;99 percent concordance with Sanger sequencing. 23andMe also showed &gt;99 percent reproducibility when tested under different laboratory conditions.



<h6 class="wp-block-heading" id="h-find-out-more">Find Out More</h6>



23andMe Health + Ancestry customers on the lastest chip who want to see their <a href="https://you.23andme.com/reports/ghr.brca_v2/">BRCA1/BRCA2 (Selected Variants) Genetic Health Risk report can go here.</a>



Not yet a customer? Find out more about 23andMe’s Health + Ancestry Service and all the other services offered to customers <a href="https://www.23andme.com/compare-dna-tests/">here</a>.



<hr class="wp-block-separator has-alpha-channel-opacity"/>



<h6 class="wp-block-heading" id="h-disclaimer">Disclaimer</h6>



**The 23andMe PGS test includes health predisposition and carrier status reports. Health predisposition reports include both reports that meet FDA requirements for genetic health risks and reports which are based on 23andMe research and have not been reviewed by the FDA. The test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults from saliva for the purpose of reporting and interpreting genetic health risks and reporting carrier status. It is not intended to diagnose any disease. Your ethnicity may affect the relevance of each report and how your genetic health risk results are interpreted. Each genetic health risk report describes if a person has variants associated with a higher risk of developing a disease, but does not describe a person’s overall risk of developing the disease. The test is not intended to tell you anything about your current state of health, or to be used to make medical decisions, including whether or not you should take a medication, how much of a medication you should take, or determine any treatment.



<h6 class="wp-block-heading" id="h-nbsp-warnings-amp-limitations">&nbsp;Warnings &amp; Limitations: </h6>



The 23andMe PGS Genetic Health Risk Report for BRCA1/BRCA2 (Selected Variants) is indicated for reporting of 44 variants in the BRCA1 and BRCA2 genes. The report describes if a person&#8217;s genetic result is associated with an increased risk of developing breast cancer and ovarian cancer. These variants also may be associated with an increased risk for prostate cancer, pancreatic cancer, and potentially other cancers. The variants included in this report do not represent the majority of the BRCA1/BRCA2 variants in people of most ethnicities. This report does not include variants in other genes linked to hereditary cancers. In addition, the absence of variants included in this report does not rule out the presence of other genetic variants that may impact cancer risk. This report is for over-the-counter use by adults over the age of 18. It provides genetic information to inform discussions with a healthcare professional. The PGS test is not a substitute for visits to a healthcare professional for recommended screenings or appropriate follow-up. Results should be confirmed by an independent genetic test prescribed by your own healthcare provider before taking any medical action. For important information and limitations regarding each genetic health risk report, visit 23andme.com/test-info.&nbsp;

23andMe Updates BRCA1/2 Report

Although nine out of 10 parents in the US agree that knowing family health history is important for knowing their own health risks, fewer than half, 38 percent, actually know that history, according to a new survey.



That’s according to a recent poll of 2,000 U.S. respondents from a nationally representative sample for age, gender, region and ethnicity, about 90 percent of whom self-identified as parents.



<figure class="wp-block-image aligncenter size-large wp-duotone-unset-1"><img loading="lazy" decoding="async" width="1024" height="379" src="http://35.88.189.111/wp-content/uploads/2023/09/9-in-10-family-history-important-1024x379.jpg" alt="An image showing that 9 in 10 parents agreed that knowing family health history is important for knowing your own health risks." class="wp-image-32166" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important-1024x379.jpg 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important-300x111.jpg 300w, https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important-768x284.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important-880x326.jpg 880w, https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important-1180x437.jpg 1180w, https://blogcms.23andme.com/wp-content/uploads/2023/09/9-in-10-family-history-important.jpg 1413w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>



<h6 class="wp-block-heading" id="h-unsure-about-family-health-history">Unsure about Family health history</h6>



Eighty-two percent of parents surveyed were concerned about the risk of unknown hereditary conditions because they don&#8217;t know more of their family’s health history.



Conducted by OnePoll on behalf of <a href="https://www.23andme.com/">23andMe</a>, the survey also suggests that American parents are as likely to have complete medical information for their father as their mother (67 percent and 64 percent respectively). However, by the next generation, those numbers drop.



Parents surveyed were less likely to have records for their paternal grandparents than they are for maternal grandparents, for instance.



<h6 class="wp-block-heading" id="h-finding-answers">Finding Answers</h6>



For those who can’t connect with their biological relatives, or who are looking for further, more in-depth<a href="https://blog.23andme.com/articles/learn-your-health-history" target="_blank" rel="noreferrer noopener"> information about their health history</a>, there are other options. Half of parents polled have researched historical and medical records to learn more about their family.&nbsp;



And 52 percent of parents polled have taken a DNA test for health information —&nbsp;something 81 percent said is important in helping fill gaps they have about their biological family’s health history.



“If you have the ability to <a href="https://blog.23andme.com/articles/family-health-history" target="_blank" rel="noreferrer noopener">discuss your family’s health history </a>with an actual living family member, don’t squander that opportunity,” said Noura Abul-Husn, VP, Genomic Health at 23andMe. “It can be a difficult conversation, and maybe they won’t have complete information to share, but every little bit can help bring you closer — and healthier — together.



“As beneficial as those conversations can be, DNA tests can also fill in the gaps, providing information even your relatives might not be aware of.”



<h6 class="wp-block-heading" id="h-dna-testing">DNA Testing</h6>



Of those who have taken a DNA test, 76 percent said they’ve adopted healthier behaviors as a result.



<figure class="wp-block-image aligncenter size-large"><img loading="lazy" decoding="async" width="1024" height="658" src="http://35.88.189.111/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-1024x658.jpg" alt="An image illustrating that 76 of those surveyed who've taken a DNA test said they have adopted healthier behaviors as a result." class="wp-image-32168" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-1024x658.jpg 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-300x193.jpg 300w, https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-768x493.jpg 768w, https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-880x565.jpg 880w, https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior-1180x758.jpg 1180w, https://blogcms.23andme.com/wp-content/uploads/2023/09/76-Adopted-Health-Behavior.jpg 1406w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>



Common DNA-inspired habits —&nbsp;for parents who have made healthy changed after taking a DNA test —&nbsp;included eating healthier (70 percent), improving stress and mindfulness (67 percent), and getting more exercise (67 percent).



DNA test or not, 46 percent of parents rate their overall health as “very healthy,” but only 39 percent strongly agree they’re in control of their health.



Roughly three in four, or 78 percent, were confident that they have the information they need to be proactive about their future health.&nbsp; 



“Genetic testing is an underutilized tool available for people to uncover important health info about their family and themselves,” added Abul-Husn. “Genetic testing can’t tell you the future, of course, but it can help you determine potential risk factors that you might not have known about, so you’re able to make better-informed choices for yourself and your family.”

Family Health History Check

23andMe and the non-profit Sickle Cell 101 have joined forces to expand our efforts in raising<a href="https://www.23andme.com/sickle-cell-awareness-program/"> awareness about people’s sickle cell carrier status</a>.



<h6 class="wp-block-heading" id="h-the-sickle-cell-awareness-program">The Sickle Cell Awareness Program</h6>



We are launching this program just as we commemorate Sickle Cell Awareness Month in September. The project will include offering the 23andMe Health + Ancestry Service for free to a limited number of individuals.* In addition, participants will have access to<a href="https://www.sc101.org/sicklecelltrait/"> Sickle Cell 101’s</a> online education tools and genetic counselors.



23andMe’s Health + Ancestry Service includes a<a href="https://www.23andme.com/topics/carrier/sickle-cell-anemia/"> Sickle Cell Anemia Carrier Status report.*</a>* This allows participants to learn their carrier status. 23andMe’s report includes extensive information about what it means to be a carrier of the sickle cell trait. But this collaboration also gives those with additional questions a place to go for answers. For instance, if a person has questions about the differences between having sickle cell trait — a carrier of sickle cell anemia with one copy of the HbS variant — versus having sickle cell disease, they can discuss this with a Sickle Cell 101 genetic counselor. Sickle Cell 101 is the largest global online platform for sickle cell education, awareness, and research.&nbsp;



“This project builds on what we’re already doing at 23andMe,” said Joyce Tung, PhD, 23andMe’s Vice President of Research. “We have research projects underway and an ongoing awareness campaign focused on sickle cell. Partnering with Sickle Cell 101 will allow us to expand that effort to more people. 23andMe is about empowering people through access to their genetic data to make more informed health decisions, which is exactly what this program offers.”



<h6 class="wp-block-heading" id="h-more-about-sickle-cell-trait-and-sickle-cell-disease">More about Sickle Cell Trait and Sickle Cell Disease</h6>



But much work is needed to raise awareness more broadly about these conditions.



The most commonly known form of sickle cell disease is sickle cell anemia. To have sickle cell anemia, one must inherit two copies of the HbS variant. This would be one copy of the HbS variant from each biological parent. People with just one copy of the HbS variant are called carriers; they’re also said to have <a href="https://www.cdc.gov/ncbddd/sicklecell/traits.html">sickle cell trait</a>. They’re not expected to have sickle cell anemia themselves. They typically do not experience any health complications. However, in rare cases, people with the sickle cell trait may experience some health impacts. You can learn more about sickle cell trait from the <a href="https://www.cdc.gov/ncbddd/sicklecell/traits.html">CDC</a> and the <a href="https://www.hematology.org/education/patients/anemia/sickle-cell-trait">American Society of Hematology</a>. You can also speak to your healthcare provider or experts at Sickle Cell 101 by contacting <a href="mailto:ask@sc101.org">ask@sc101.org</a>.&nbsp;



Importantly, carriers can pass their variant on to their future children. If their partner has the HbS variant or another variant in the HBB gene, there’s a 25 percent chance that each child may have sickle cell anemia or a related blood disorder.&nbsp;&nbsp;



Other forms of sickle cell disease are also caused by variants in the HBB gene. Instead of having two copies of the HbS variant, like people with sickle cell anemia, people with other types of sickle cell disease have one copy of the HbS variant and another variant elsewhere in the HBB gene. Examples of other types of sickle cell disease include hemoglobin sickle cell disease and sickle beta thalassemia disease.



<div style="float: right; text-align: justified; width: 400px; background-color: #eee; padding: 15px; margin-left: 10px;">Sickle Cell Facts You Need to Know


• A person must have two copies of the HbS variant in the HBB gene to have sickle cell anemia. 

• Typical signs and symptoms of sickle cell anemia include episodes of pain, and frequent infections. 

• People with one copy of the HbS variant are carriers of sickle cell disease (sickle cell trait) who can pass the variant on to their future children. 

• About 1 in 13 African Americans have the HbS variant but the variant can also be found in people from the Caribbean, the Mediterranean, and part of Central and South America. </div>



<h6 class="wp-block-heading" id="h-building-awareness-expanding-research">Building Awareness, Expanding Research</h6>



This project builds on <a href="https://www.23andme.com/sickle-cell/">23andMe’s ongoing awareness program</a> with the<a href="https://www.msm.edu/"> Morehouse School of Medicine</a> and the <a href="https://www.sicklecellga.org/">Sickle Cell Foundation of Georgia, Inc. (SCFG)</a>.&nbsp; The foundation also created a dedicated webpage for program participants. In addition, anyone who is participating in the 23andMe program to access the site and <a href="https://www.livingwellresources.org/geneticcounseling">connect with genetic counselors at SCFG via the following link: Genetic Counseling | Mysite</a>. From those efforts, we learned participants wanted to be able to ask questions about their status. Along with raising awareness about the importance of sickle cell carrier status testing and improving access to testing, this effort will offer additional online resources for people who may have sickle cell trait or have sickle cell disease.



Beyond raising awareness, 23andMe is also committed to learning more about sickle cell through our research. Our scientists are working on sickle cell research, most recently collaborating with scientists at the <a href="https://www.nih.gov/">National Institutes of Health</a> and <a href="https://www.hopkinsmedicine.org/som/">Johns Hopkins University School of Medicine</a>. The study’s <a href="https://blog.23andme.com/articles/new-research-on-sickle-cell-trait">initial findings</a> were presented at the American Society of Hematology’s annual meeting in 2022, but have not yet been published. It is now the largest and most diverse genetic study of sickle cell trait.&nbsp;



More broadly, this effort will help with 23andMe’s efforts to improve the diversity of our research, as participants in the program have the opportunity to consent to participate in research if they choose, which will enable other studies like the Sickle Cell trait research above.&nbsp;



<figure class="wp-block-image size-large"><img loading="lazy" decoding="async" width="1024" height="538" src="http://35.88.189.111/wp-content/uploads/2023/06/Open-Graph-Image-1024x538.png" alt="An illustration for 23andMe's Sickle Cell Carrier Statues Awareness Program." class="wp-image-31918" srcset="https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image-1024x538.png 1024w, https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image-300x158.png 300w, https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image-768x403.png 768w, https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image-880x462.png 880w, https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image-1180x620.png 1180w, https://blogcms.23andme.com/wp-content/uploads/2023/06/Open-Graph-Image.png 1200w" sizes="auto, (max-width: 1024px) 100vw, 1024px" /></figure>



<h6 class="wp-block-heading" id="h-23andme-s-sickle-cell-anemia-carrier-status-report">23andMe’s Sickle Cell Anemia Carrier Status Report**</h6>



23andMe’s<a href="https://www.23andme.com/topics/carrier/sickle-cell-anemia/"> Sickle Cell Anemia Carrier Status Report</a>, which meets FDA requirements for clinical and analytical validity, looks at the HbS variant in the HBB gene, which is linked to sickle cell anemia.



Sickle cell anemia is the most severe form of sickle cell disease. Three-hundred-million people worldwide and one in 13 Black and or African Americans in the United States have sickle cell trait, making them carriers for sickle cell anemia.



In addition to informing people if they have one copy of the HbS variant and are carriers for sickle cell anemia, 23andMe&#8217;s report can also tell individuals if they have two copies of the tested variant and if they are at risk of developing symptoms of the condition. But the report does not describe one’s overall risk of developing symptoms.&nbsp;



Because the HbS variant is more common in certain populations, the Sickle Cell Anemia report is most relevant for people of African descent, as well as people of Middle Eastern and South Asian descent, as well as people from the Caribbean, the Mediterranean, and parts of Central and South America.



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<h6 class="wp-block-heading" id="h-eligibility">*Eligibility:</h6>



· You live in the United States



· You are at least 18 years old



· You have African ancestry; identify as Black, African American, or of African descent; or you have ancestry from a region where sickle cell disease is common†



· You are willing to provide a saliva sample for DNA testing



· You are willing to agree to 23andMe’s<a href="https://www.23andme.com/legal/terms-of-service/"> Terms of Service</a> and<a href="https://www.23andme.com/legal/privacy/"> Privacy Statement</a>



· Research consent is optional and not required for participation in the program



†Regions include Africa, the Middle East, South Asia, the Caribbean, Mediterranean Europe/Asia, Central and South America.



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<h6 class="wp-block-heading" id="h-note">Note:</h6>



**The 23andMe PGS test uses qualitative genotyping to detect select clinically relevant variants in the genomic DNA of adults for the purpose of reporting carrier status and reporting and interpreting genetic health risks. The relevance of each report may vary based on ethnicity. Our carrier status reports can be used to determine carrier status, but cannot determine if you have two copies of any genetic variant. These carrier reports are not intended to tell you anything about your risk for developing a disease in the future or anything about the health of your fetus, or your newborn child’s risk of developing a particular disease later in life. For certain conditions, we provide a single report that includes information on both carrier status and genetic health risk. For important information and limitations regarding other genetic health risk reports and carrier status reports, click <a href="https://www.23andme.com/test-info/">here</a>.



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Health + Traits — Page 7